Launching May 2026  ·  Reserve →
A woman in late afternoon light

Brain fog. Hot flashes. Weight gain.

Physician-led care, prescribed in 24 hours.

Start your visit — $49

Licensed in 50 states · LegitScript certified · Prescribed by U.S. physicians

What we treat

Two programs.

What we treat, what it costs.

Program 01

HRT

Hormone Replacement Therapy

For perimenopause and menopause symptoms.

Hot flashes, night sweats, sleep

Brain fog, mood, anxiety

Joint pain, vaginal dryness, libido

$99/month

Billed $297 quarterly. Free shipping every 90 days.

Learn more →

Program 02

Weight Management

Compounded Semaglutide Protocol

Compounded semaglutide with B12 and glycine. Weekly subcutaneous injection.

Personalized titration, dose adjustments included

Monthly physician check-ins

Compounded by Strive Pharmacy

$199/month

Billed monthly. Free shipping every month.

Learn more →
A board-certified physician — illustrative

Your prescriber

A board-certified physician on your chart.

Every Therisse prescription is written by a U.S.-licensed physician from MD Integrations — a practice dedicated to Therisse patients. Not a nurse practitioner. Not an algorithm. The same prescriber reviews your intake, makes the clinical call, and answers your messages through treatment.

Board-certified physicians across all 50 states. No algorithms in the prescribing chain.

How Therisse compares

Care that checks every box.

Most telehealth in this category runs on algorithmic intake, generic protocols, and dose-based upsells. Therisse uses board-certified physicians and transparent fees.

Other

Therisse
No 6-month waitlist
No nurse practitioners
No generic protocols
No dose-based upsells

How it works

Intake to medication, in days.

01

Online intake

6–10 minutes. Symptoms, medical history, current medications.

02

$49 visit fee

Pay for the visit. Nothing else is charged until you're approved.

03

Physician review

A U.S.-licensed doctor reviews within 24 hours.

04

Strive ships

If approved, medication ships in 3–5 business days.

Most patients get a decision within 24 hours.

See the full process →

FAQ

Five questions we get most.

Is Therisse legitimate?

Yes. We're LegitScript-certified, which means our telehealth practice and pharmacy partner are audited and monitored against national standards for licensure, safety, and advertising.

Our medications are dispensed by Strive Compounding Pharmacy, a triple-accredited 503A pharmacy regulated by state pharmacy boards. We're transparent about who prescribes (MD Integrations), who dispenses (Strive), and who operates the platform (Ironoak Holdings LLC).

Do I need bloodwork?

Not to start. The decision to begin HRT is made primarily on symptoms, history, and risk factors — current ACOG and NAMS guidance does not require baseline labs for the average symptomatic patient under 60.

Your physician may order labs later if there's a specific clinical reason (e.g., unexplained bleeding, persistent symptoms, monitoring testosterone). You'd pay the lab directly; we don't mark up lab work or bundle it into the subscription.

How fast does my medication ship?

From physician approval, Strive Pharmacy typically dispenses within 2 business days and your shipment arrives within 3–5 business days. Most patients receive their first delivery within a week of finishing intake.

You'll get tracking the moment it ships. All packaging is plain, unmarked, and discreet.

Do you take insurance?

No. We don't bill insurance for visits or medication, and we don't accept HSA/FSA for compounded products.

We chose this because insurance reimbursement on compounded HRT and weight management is unreliable and adds weeks of paperwork. Charging cash directly lets us keep visits short, prescribers focused, and pricing transparent.

Is this the same as Ozempic or Wegovy?

The active ingredient — semaglutide — is the same. Ozempic® and Wegovy® are FDA-approved, commercially manufactured products from Novo Nordisk. Our medication is compounded semaglutide, prepared by a licensed 503A pharmacy.

Therisse is not affiliated with or endorsed by Novo Nordisk. Ozempic® and Wegovy® are registered trademarks of Novo Nordisk A/S.

Two minutes to start.
24 hours to a decision.

Licensed in 50 states · LegitScript certified · Refundable if not approved