HRT & GLP-1 weight loss • From $89/mo
Board-certified physicians • 50+ states • Cancel anytime
Hormone & Weight Care, Reimagined
Personalized HRT and GLP-1 weight loss. Board-certified physicians. Delivered to your door.
No insurance needed • Cancel anytime • 50+ states
24/7
Physician Access
2–4
Weeks to Results
50+
States Licensed
$0
Hidden Fees
The Problem
Perimenopause, menopause, and the metabolic changes that come with them aren't something to "just get through." They are medical conditions with real, proven treatments.
Therisse exists because you deserve better than being told it's "just stress" or "just eat less."
"I spent three years thinking something was wrong with me before a doctor finally said the word 'perimenopause.'"
— A story we hear every single day
Recognize Yourself?
Sudden waves of heat that disrupt your day and steal your sleep.
Words on the tip of your tongue. Tasks that used to be easy now feel impossible.
Irritability, sadness, or anxiety that feels out of character and out of control.
Your body is changing despite the same diet and exercise. Hormonal shifts and metabolic resistance often need medical support — not another diet.
Tossing, turning, waking at 3am. True rest feels like a distant memory.
Exhaustion that sleep doesn't fix. Running on empty has become your normal.
A shift in desire that can feel confusing, frustrating, and isolating.
Aches and stiffness that appeared out of nowhere. Hormones may be the hidden cause.
Sound familiar? You don't have to keep pushing through.
Simple, Not Simplified
10-minute health assessment from home. Your symptoms, history, and goals.
One-on-one video consultation with a board-certified doctor who specializes in women's health.
HRT, GLP-1, or both — prescribed and delivered to your door monthly. Ongoing monitoring included.
Who You'll Work With
Endocrinology, OB/GYN, or internal medicine with advanced HRT training.
Dedicated to hormonal health, HRT, and medical weight management.
One doctor who knows your history. No revolving door.
HIPAA compliant • physician-prescribed • Licensed in all 50 states
Everything You Need
Physician consultations, compounded medications, and ongoing care included. No hidden fees. Cancel anytime.
Hormone Program
Bioidentical estradiol, progesterone, and testosterone — tailored to you.
HRT Single
Progesterone or estradiol
$89/mo
HRT Complete
Estradiol + progesterone
$149/mo
Weight Loss Program
Compounded semaglutide (same ingredient as Ozempic®) at a fraction of the cost.
Starting
0.25 – 0.5mg weekly
$199/mo
Standard
1mg weekly
$249/mo
Maximum
1.7 – 2.4mg weekly
$299/mo
Board-Certified
Physician
Monthly
Consultations
Compounded
Medications
HIPAA
Compliant
Ongoing
Monitoring
Direct
Messaging
Cancel anytime · No contracts · No cancellation fees
"This isn't the end of something.
It's the beginning of everything."
Common Questions
For most women, yes. The medical consensus has shifted significantly in the past decade. Major medical organizations, including the North American Menopause Society and the Endocrine Society, support HRT for symptomatic women who are within 10 years of menopause onset. Your Therisse physician will conduct a thorough evaluation of your personal health history, risk factors, and symptoms to determine whether HRT is appropriate and safe for you specifically.
Much of the fear around HRT stems from a 2002 study (the Women's Health Initiative) that has since been largely reinterpreted. Subsequent research has shown that for women under 60 or within 10 years of menopause, the benefits of HRT — including relief from symptoms, bone protection, and cardiovascular benefits — generally outweigh the risks. Modern HRT formulations, including bioidentical hormones and transdermal delivery, carry a more favorable safety profile than the oral conjugated estrogens studied decades ago.
Many women notice improvement in sleep, hot flashes, and mood within 2–4 weeks. Full benefits typically develop over 2–3 months as your body adjusts to optimized hormone levels. Your physician will check in regularly and make adjustments to ensure you're getting the best possible results.
No referral is needed. Therisse is a direct-to-consumer telehealth platform. You can start your assessment today and be connected with a board-certified physician who specializes in menopause care — without needing to wait for a referral or navigate insurance bureaucracy.
For HRT, we prescribe bioidentical estradiol, progesterone, and testosterone when appropriate. For weight loss, we prescribe compounded semaglutide (the same active ingredient in Ozempic® and Wegovy®) with B12 and glycine. All medications are compounded by a licensed US pharmacy and personalized to your needs. Compounded medications are not FDA-approved but are prescribed by licensed physicians based on individual patient needs.
Yes. There are no long-term contracts and no cancellation fees. If Therisse isn't right for you, you can cancel your membership at any time through your account. Your physician will also provide guidance on safely tapering any prescribed treatment if needed.
Start your personalized hormone therapy or weight loss journey today.
Get Started — from $89/moNo insurance needed • Cancel anytime • Delivered to your door