Weight management

Compounded semaglutide

Once-weekly semaglutide with B12 and glycine, prescribed by a U.S.-licensed physician and shipped to your door.

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Compounded semaglutide vial

Refunded in full if a physician doesn't approve you

What it is

One weekly injection, dosed for you.

Quiets appetite

Works with your body's own GLP-1 appetite signaling, so hunger takes up less of your day.

Slows stomach emptying

Food leaves your stomach more slowly, which steadies how full you feel after meals.

Fuller, sooner

You feel satisfied on less, and stay satisfied longer between meals.

Ours is compounded semaglutide with B12 (cyanocobalamin) and glycine, prepared by a licensed 503A compounding pharmacy. Glycine is a stabilizer; B12 is included because GLP-1 medications can mask or exacerbate B12 deficiency, particularly in women over 40.

What the research shows

The largest trial, in one chart.

1,961 adults, 68 weeks, published in the New England Journal of Medicine.

Mean change in body weight over 68 weeks

0% -5% -10% -15% -2.4% placebo -14.9% semaglutide Week 0 Week 68

-14.9%

average change in body weight at 68 weeks, vs -2.4% with placebo

86%

of participants on semaglutide lost at least 5% of their body weight

Source: Wilding et al., New England Journal of Medicine (2021), the STEP 1 trial of once-weekly semaglutide 2.4 mg plus lifestyle intervention. Curves are illustrative between the reported endpoints. Trial data are for FDA-approved semaglutide (Wegovy®); our medication is compounded semaglutide. Individual results vary.

How you take it

Once a week, at home.

Once a week

A small under-the-skin injection you give yourself at home, with a short, fine needle.

Starts low, moves slowly

Your physician raises the dose month by month based on your response. Going slowly keeps the common side effects manageable.

Arrives ready

Ships in cold-chain packaging with the syringes and alcohol swabs you need.

Every dose change is a clinical decision made with your physician at a monthly check-in, and you can message your care team between check-ins whenever something feels off.

Safety

The honest version, up front.

Side effects are real, mostly digestive, mostly early, and mostly fade. Here is how often they happened in the same 68-week trial.

Participants reporting each side effect over 68 weeks

Semaglutide Placebo Nausea 44.2% 17.4% Diarrhea 31.5% 15.9% Vomiting 24.8% 6.6% Constipation 23.4% 9.5%

Source: Wilding et al., New England Journal of Medicine (2021), STEP 1 trial (semaglutide n=1,306, placebo n=655). Most events were mild to moderate, occurred early or during dose increases, and resolved without stopping treatment.

Less common but more serious risks include pancreatitis, gallbladder issues, and rare hypoglycemia. Your physician screens for risk factors during intake, and you can message your care team any time something feels wrong.

One thing we state plainly: the active ingredient, semaglutide, is the same as in Ozempic® and Wegovy®, which are FDA-approved products from Novo Nordisk. Ours is compounded semaglutide, prepared by a licensed 503A pharmacy, and compounded medications are not FDA-approved.

FAQ

Questions, answered.

Is this the same as Ozempic or Wegovy?

The active ingredient, semaglutide, is the same. Ozempic® and Wegovy® are FDA-approved, commercially manufactured products from Novo Nordisk. Our medication is compounded semaglutide, prepared by a licensed 503A pharmacy.

Why B12 and glycine?

Glycine is an amino acid we add as a stabilizer; it has no notable pharmacological effect at compounded concentrations. B12 is included because GLP-1 medications can mask or exacerbate B12 deficiency, particularly in women over 40, and many of our patients are already marginally low.

Neither B12 nor glycine alters the mechanism of semaglutide. The combination is a common 503A compounding choice for tolerability and shelf stability.

Will I actually lose weight?

Probably, if you're a clinical fit and you stay on the protocol. In published trials of semaglutide for weight management, average weight loss over 68 weeks ranged from roughly 10% to 15% of body weight, depending on dose and adherence.

Outcomes vary based on starting weight, dose, side-effect tolerance, sleep, stress, and diet. Some women lose more, some lose less, some plateau and need a dose change. We don't promise an outcome. We promise an honest titration and a prescriber who returns your messages.

How is my dose decided?

Your physician starts you low and titrates monthly based on your response and tolerability. A dose change is a clinical decision made between you and your physician.

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Keep reading

From the learn library.

Menopause weight gain: why it happens and what helps

Why midlife weight change is metabolic, what HRT does and doesn't do, and where GLP-1 medication fits.

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The full learn library

Plain-language articles on hormones, menopause, and midlife metabolic health, written for decisions, not clicks.

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Every question we get asked

Eligibility, bloodwork, shipping, insurance, and what happens if you're not approved.

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Two minutes to start. 24 hours to a decision.

Answer a few questions and a licensed physician takes it from there.

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