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Hot flashes.
3 a.m. wake-ups.
Weight gain.

These are treatable. HRT and weight management prescribed online by a U.S.-licensed physician, shipped to your door.

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Plans from $99/month · HSA/FSA accepted · Licensed in 50 states

Where to begin

What's your goal?

What we prescribe

Real medication, compounded for you.

Prescribed by a U.S.-licensed physician, filled by a licensed 503A pharmacy.

Bi-est cream metered-dose dispenser, illustrative render
HRT

Bi-est cream

Estriol and estradiol in a metered-dose topical cream.

Progesterone capsules bottle
HRT

Progesterone

Oral micronized progesterone capsules.

Compounded semaglutide vial
Weight management

Semaglutide

Compounded semaglutide with B12 and glycine.

* Product images for illustrative purposes only.

How it works

Three steps, a few days.

01

Online intake

A few minutes. Symptoms and history.

02

Physician review

A licensed doctor reviews your chart.

03

Your order ships

Delivered in 3–5 days.

If not approved, your payment is refunded in full.
FAQ

Questions, answered.

Is Therisse legitimate?

Yes. We're LegitScript-certified, which means our telehealth practice and pharmacy partner are audited and monitored against national standards for licensure, safety, and advertising.

What do you treat?

Perimenopause and menopause symptoms (hot flashes, night sweats, broken sleep, mood, brain fog) and midlife weight. Our HRT program covers bi-est cream and oral micronized progesterone; our weight program covers compounded semaglutide with B12 and glycine. All prescribed by a U.S.-licensed physician and compounded by a licensed 503A pharmacy.

What does it cost?

HRT is $99 a month, billed $297 every 90 days when your 90-day supply ships, with free shipping. Weight management is $229 a month, flat, at every dose, shipping included. Your first checkout includes a separate one-time initial consult fee ($30 HRT, $20 weight management). If a physician doesn't approve you, everything is refunded in full.

Is compounded medication FDA-approved?

No. Compounded medications are not FDA-approved. They are prepared by a licensed 503A compounding pharmacy to a physician's prescription.

How fast does my medication ship?

From physician approval, the pharmacy typically dispenses within 2 business days and your shipment arrives within 3–5 business days. All packaging is plain, unmarked, and discreet.

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